Timothy Wang Laboratory
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Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis

Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis

Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis

 Chang W, Wang H, Kim W, Liu Y, Deng H, Liu H, Jiang Z, Niu Z, Sheng W, Nápoles OC, Sun Y, Xu J, Sepulveda A, Hayakawa Y, Bass AJ, Wang TC. Cell Stem Cell. 2020 May 7;26(5):739-754.e8. Epub 2020 Mar 5.PMID: 32142681  

PD-1 Signaling Promotes Tumor-Infiltrating Myeloid-Derived Suppressor Cells and Gastric...

Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis

Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis

 Kim W, Chu TH, Nienhüser H, Jiang Z, Del Portillo A, Remotti HE, White RA, Hayakawa Y, Tomita H, Fox JG, Drake CG, Wang TC. Gastroenterology. 2021 Feb;160(3):781-796. Epub 2020 Oct 29.PMID: 33129844 

Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche

Hormonal Suppression of Stem Cells Inhibits Symmetric Cell Division and Gastric Tumorigenesis

Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumor

 Middelhoff M, Nienhüser H, Valenti G, Maurer HC, Hayakawa Y, Takahashi R, Kim W, Jiang Z, Malagola E, Cuti K, Tailor Y, Zamechek LB, Renz BW, Quante M, Yan KS, Wang TC. Nat Commun. 2020 Jan 8;11(1):111. PMID: 31913277 

Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumor

Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumor

Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumor

Renz BW, Tanaka T, Sunagawa M, Takahashi R, Jiang Z, Macchini M, Dantes Z, Valenti G, White RA, Middelhoff MA, Ilmer M, Oberstein PE, Angele MK, Deng H, Hayakawa Y, Westphalen CB, Werner J, Remotti H, Reichert M, Tailor YH, Nagar K, Friedman RA, Iuga AC, Olive KP, Wang TC. Cancer Discov. 2018 Nov;8(11):1458-1473. Epub 2018 Sep 5.PMID: 30185628  

The Tuft Cell-ILC2 Circuit Integrates Intestinal Defense and Homeostasis

Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumor

The Tuft Cell-ILC2 Circuit Integrates Intestinal Defense and Homeostasis

 Hayakawa Y, Wang TC. Cell. 2018 Jul 12;174(2):251-253. PMID: 30007413  

β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer

Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumor

The Tuft Cell-ILC2 Circuit Integrates Intestinal Defense and Homeostasis

Renz BW, Tanaka T, Sunagawa M, Takahashi R, Jiang Z, Macchini M, Dantes Z, Valenti G, White RA, Middelhoff MA, Ilmer M, Oberstein PE, Angele MK, Deng H, Hayakawa Y, Westphalen CB, Werner J, Remotti H, Reichert M, Tailor YH, Nagar K, Friedman RA, Iuga AC, Olive KP, Wang TC. Cancer Discov. 2018 Nov;8(11):1458-1473. Epub 2018 Sep 5.PMID: 30185628  

Stem cells and origins of cancer in the upper gastrointestinal tract

Stem cells and origins of cancer in the upper gastrointestinal tract

Stem cells and origins of cancer in the upper gastrointestinal tract

 Hayakawa Y, Nakagawa H, Rustgi AK, Que J, Wang TC. Cell Stem Cell. 2021 Aug 5;28(8):1343-1361. Epub 2021 Jun 14.PMID: 34129814  

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